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. 2015 Mar 3;9:1281–1292. doi: 10.2147/DDDT.S71557

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© 2015 Iman et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Girinimbine inhibits HUVECs’ invasion in dose-dependent manner.

Notes: Compared to the control, girinimbine treatment resulted in significant inhibition of HUVECs through coating buffer, 0.1× and 1× BME. Data are given as number of invading cells and are means of two different assays (each carried out in triplicate). Significance is expressed as ***P<0.001; **P<0.01.

Abbreviations: HUVECs, human umbilical vein endothelial cells; BME, basement membrane extract; EBM, endothelial basal medium; EGM, endothelial growth medium.