Table 2.
Percentage of embryo viability following treatment with girinimbine
| Treatment | Number of embryos | Number of fatalities at 48 and 72 hpf | Percentage of viability (%) |
|---|---|---|---|
| Girinimbine, 20 μg/mL | 30 | 5*; 1** | 83.2%*; 80%** |
| SU5416 (positive control) 0.25 μg/mL | 30 | 4*; 2** | 86.6%; 80% |
| DMSO (vehicle control) 1% | 30 | 2 | 93.3% |
Notes:
Number of fatalities observed at 48 hpf (after 24 hour treatment).
Number of fatalities observed at 72 hpf (24 hour treatment followed by 24 hour recovery in system water).
Abbreviations: DMSO, dimethyl sulfoxide; hpf, hours post fertilization.