Table 3.
New Cell Phenotypes in Monkeys With Short Survivals After Single BrdU Injections
| A. | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Post-Brdu survival (BrdU #) | NG2+ cells | NG2− cells | NOT perivasc | Combined cell types | |||||||
| Per-Elu | Pldv | Pld | NG2+ unka | perivasc | Total NG2+ | All NG2+ perivascb | All perivascc | NG2+ multi-branchd | NG2+ NOT multi-branche | ||
| 2 d (121) | 43 (52) | 5 (6) | 18 (22) | 28 (34) | 1 (1) | 6 (6) | 94 (114) | 48 | 49 | 23 | 71 |
| 2 d (92) | 40 (37) | 0 (0) | 10 (9) | 40 (37) | 3 (3) | 7 (6) | 90 (83) | 40 | 43 | 10 | 80 |
| 2 w (109) | 48 (52) | 6 (7) | 21 (23) | 8 (9) | 5 (5) | 13 (14) | 83 (91) | 54 | 59 | 28 | 56 |
| 6 w (115) | 16 (18) | 29 (33) | 34 (39) | 9 (10) | 3 (4) | 10 (11) | 86 (99) | 44 | 48 | 63 | 24 |
| 6 w (119) | 22 (26) | 13 (16) | 34 (41) | 6 (7) | 3 (3) | 19 (23) | 74 (88) | 35 | 38 | 48 | 28 |
| B. | |||
|---|---|---|---|
| Cell type or combination | Lower | Estimate | Upper |
| All NG2/BrdU | 83 | 86 | 89 |
| Per-Elu | 29 | 33 | 37 |
| Pldv | 9 | 11 | 14 |
| Pld | 21 | 24 | 28 |
| NG2+ unknown | 14 | 17 | 21 |
| NG2− perivascular | 2 | 3 | 5 |
| NG2− NOT perivascular | 9 | 11 | 14 |
| NG2+ perivascular combined | 40 | 44 | 48 |
| All perivascular | 43 | 47 | 52 |
| NG2+ Multi-branched | 31 | 35 | 39 |
| NG2+ NOT Multi-branched | 46 | 51 | 55 |
A: Percentages of BrdU+ cell totals for NG2+ and NG2− cell types and cell combinations from monkeys with single BrdU injections and short survivals after BrdU. Cell counts are in parentheses and italicized. 2 d, 2 day; 2 w, 2 week; 6 w, 6 week; a, NG2+ unknown (not perivascular, not multi-branched); b, Per-Elu and Pldv; c, Per-Elu, Pldv, and NG2− perivascular; d, Pldv and Pld; e, Per-Elu, and NG2+ unk. B: Estimated mean percentages and ranges of new cell phenotypes and combinations based on binomial regression modeling.