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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Am J Hematol. 2014 May 16;89(8):813–818. doi: 10.1002/ajh.23751

Table 3.

Multivariate Cox Proportional Hazard Regression Analysis for Overall Survival and Leukemia-free Survival.

Overall survival Leukemia-free Survival
Variables Hazard ratio (95% CI) p Hazard ratio (95% CI) P
Hemoglobin level
<10 vs. ≥ 10 g/dl
1.599 (1.214 – 2.106) 0.001 1.760 (1.151 – 2.692) 0.009
White blood cell count
≥13 vs. <13 x10^9/L
1.707 (1.184 – 2.461) 0.004 1.141 (0.858 – 1.979) 0.224
Platelet count
<100 vs. ≥ 100 x10^9/L
1.232 (1.124 – 1.656) 0.039 0.946 (0.783 – 1.355) 0.201
Absolute monocyte count
≥3 vs. <3x10^9/L
1.5 (1.148 – 1.966) 0.023 1.612 (1.024 – 2.754) 0.045
Circulating Immature Myeloid Cells
Presence vs. Absence
1.405 (1.165 – 1.854) 0.016 1.758 (1.211 – 2.807) 0.018
Bone marrow blasts
≥10 vs. <10%
1.023 (0.829 – 1.374) 0.124 2.377 (1.537 – 3.676) <0.001
Cytogenetic risk categories
- Intermediate vs. Low 1.493 (1.093 – 2.554) 0.043 2.693 (1.593 – 4.554) 0.008
- High vs. Low 3.360 (2.493 – 5.285) 0.001 3.802 (2.268 – 6.804) <0.001