Table 3.
Predictors of having (prevalence) WHI Prolapse Grade 2 or 3 in whites, blacks, and Hispanics
| Baseline Characteristic |
White | Black | Hispanic | ||||||
|---|---|---|---|---|---|---|---|---|---|
| OR* | 95% CI | p-value | OR* | 95% CI | p-value | OR* | 95% CI | p-value | |
| Age | 1.03 | (1.02, 1.04) | <.0001 | 1.01 | (0.97, 1.06) | 0.66 | 1.02 | (0.98, 1.07) | 0.38 |
|
Parity (vs. Never had a term pregnancy) |
<.0001 | 0.10 | 0.11 | ||||||
| 1 | 4.70 | (2.56, 8.63) | 0.98 | (0.21, 4.64) | 2.00 | (0.36, 11.05) | |||
| 2 | 5.74 | (3.31, 9.97) | 1.61 | (0.43, 6.03) | 2.07 | (0.43, 10.05) | |||
| 3 | 6.27 | (3.63, 10.84) | 1.21 | (0.30, 4.89) | 1.07 | (0.20, 5.65) | |||
| 4 | 7.63 | (4.40, 13.22) | 1.08 | (0.21, 5.64) | 2.67 | (0.56, 12.75) | |||
| 5+ | 10.04 | (5.82, 17.32) | 3.39 | (0.93, 12.30) | 3.52 | (0.78, 15.92) | |||
|
Smoking (vs. Never smoked) |
<.0001 | 0.50 | 0.51 | ||||||
| Past smoker | 0.76 | (0.65, 0.88) | 0.70 | (0.35, 1.38) | 1.28 | (0.68, 2.43) | |||
| Current smoker | 0.60 | (0.44, 0.81) | 0.66 | (0.23, 1.84) | 1.75 | (0.60, 5.06) | |||
|
Moderate/Severe constipation |
0.83 | (0.62, 1.11) | 0.20 | 1.73 | (0.68, 4.43) | 0.27 | 0.62 | (0.25, 1.53) | 0.28 |
| Asthma | 1.10 | (0.83, 1.47) | 0.51 | 1.95 | (0.69, 5.47) | 0.23 | 1.63 | (0.65, 4.05) | 0.31 |
| Emphysema | 1.15 | (0.77, 1.71) | 0.50 | - | - | 0.04 | 1.60 | (0.32, 8.11) | 0.59 |
|
Total hormone usage (vs. Never used) |
0.36 | 0.42 | 0.45 | ||||||
| Past user | 0.89 | (0.74, 1.07) | 0.91 | (0.37, 2.28) | 0.95 | (0.45, 2.02) | |||
| Current user | 0.88 | (0.63, 1.23) | 2.22 | (0.71, 6.96) | 0.41 | (0.09, 1.89) | |||
|
Incontinence (vs. Never) |
<.0001 | 0.52 | 0.27 | ||||||
| Stress | 0.97 | (0.79, 1.20) | 0.91 | (0.32, 2.58) | 1.83 | (0.93, 3.62) | |||
| Urge | 1.47 | (1.21, 1.79) | 1.27 | (0.59, 2.73) | 1.22 | (0.53, 2.83) | |||
| Mixed | 1.27 | (1.01, 1.60) | 2.12 | (0.65, 6.85) | 0.76 | (0.21, 2.76) | |||
| Other | 1.38 | (0.99, 1.93) | 2.34 | (0.73, 7.52) | 2.46 | (0.71, 8.51) | |||
|
Waist circumference > 88 cm |
1.19 | (0.98, 1.45) | 0.08 | 1.81 | (0.75, 4.40) | 0.19 | 1.60 | (0.75, 3.39) | 0.22 |
| Physical activity | 0.97 | (0.92, 1.03) | 0.36 | 1.12 | (0.89, 1.41) | 0.34 | 1.18 | (0.96, 1.45) | 0.13 |
|
BMI (vs. <25 kg/m2) |
<.0001 | 0.10 | 0.09 | ||||||
| 25-<30 kg/m2 | 1.64 | (1.34, 2.02) | 0.72 | (0.29, 1.79) | 2.87 | (1.03, 8.05) | |||
| ≥ 30 kg/m2 | 1.87 | (1.44, 2.43) | 0.32 | (0.10, 1.02) | 2.22 | (0.67, 7.33) | |||
*
multi-variable adjusted OR from multi-variate logistic regression analysis
*
predictors and outcome measured at baseline