Table 2.

The characteristics of liver metastasis

	Centrally located	Peripherally located	P values
	( n = 24)	( n = 135)
CEA level before hepatectomy (ng/ml)	366.2 ± 205.5 (0.88 to 4,280.0)	109.9 ± 53.2 (0.50 to 7,025.0)	0.095
Interval of hepatic metastasisa
Synchronous	17 (70.8%)	87 (64.4%)	0.544
Metachronous	7 (29.2%)	48 (35.6%)
Involved segment(s)
Single	3 (12.5%)	56 (41.5%)	0.006
Multiple	21 (87.5%)	79 (58.5%)
Lobar distribution
Unilobar	6 (25.0%)	108 (80.0%)	0.000
Bilobar	18 (75.0%)	27 (20.0%)
Maximal diameter of the largest metastasis (cm)	5.9 ± 0.8 (1.2 to 17.9)	3.0 ± 2.4 (0.3 to 10.8)	0.000
Number of metastasis
Solitary	10 (41.7%)	91 (67.4%)	0.016
Multiple	14 (58.3%)	44 (32.6%)
Differentiation of metastasis
Well	5 (20.8%)	10 (7.4%)	0.113
Moderately	18 (75.0%)	120 (88.9%)
Poorly	1 (4.2%)	5 (3.7%)

^aThe metachronous type was defined as when the metastasis was noted for 3 months or more after resection of primary colorectal cancer.