Table 1.
Characteristics1 | Males (n = 1,085) | Females (n = 954) |
---|---|---|
Age (yrs) | 50.8 ± 11.0 | 48.8 ± 9.8 |
Year at enrollment (%) | ||
1997-1999 | 70.2 | 65.6 |
2002 | 8.9 | 10.5 |
2008-2010 | 20.8 | 23.9 |
Serum biomarker levels | ||
PGI (ng/mL) | 109.3 ± 57.1 | 92.6 ± 47.7 |
PGII (ng/mL) | 17.3 ± 14.0 | 14.0 ± 10.9 |
PGI/II ratio | 9.1 ± 9.1 | 9.9 ± 10.0 |
Gastrin-17 (pmol/L) | 3.5 ± 9.7 | 4.3 ± 13.1 |
Anti-H. pylori IgG (EIU) | 42.0 ± 33.9 | 40.4 ± 32.6 |
Baseline histopathologies (%) | ||
Normal mucosa/mild non-atrophic gastritis | 14.0 | 18.1 |
Moderate non-atrophic gastritis | 22.8 | 27.6 |
Severe non-atrophic gastritis | 33.7 | 34.5 |
Mild atrophic gastritis | 4.5 | 4.4 |
Moderate atrophic gastritis | 10.7 | 7.0 |
Severe atrophic gastritis | 7.0 | 4.3 |
Low grade dysplasia | 7.2 | 3.8 |
High grade dysplasia | 0.1 | 0.3 |
Median (range) length of follow-up time (yrs) | 2.3 (0.4-7.6) | 2.2 (0.4-7.6) |
Number of follow-up visits (%) | ||
1 | 60.8 | 63.0 |
2 | 28.5 | 30.1 |
3 | 8.4 | 6.2 |
4 | 2.3 | 0.7 |
Mean ± STD, unless otherwise indicated.
Abbreviations: H. pylori: Helicobacter pylori; PG: pepsinogen.