Table 2.
Confusion matrices showing the accuracy of wakeful EEG organization (top two sub-tables) and fMRI command following (CF) (bottom sub-table) in correctly identifying patients considered to be conscious (MCS/EMCS) or unconscious (VS) based on standard clinical behavioral evaluations. Fisher’s exact test (one-tailed) revealed significant correlation between EEG background organization and bedside diagnosis regardless where the threshold for degree of EEG background abnormalities are drawn. No correlation was found between evidence for command following on fMRI and behavioral diagnosis.
Behavioral diagnosis | ||||
---|---|---|---|---|
MCS/EMCS | VS | total | ||
Awake EEG background |
normal/mild | 24 | 2 | 26 |
mod & severe | 12 | 6 | 18 | |
total | 36 | 8 | 44 | |
*Fisher’s exact test (one tailed) p=0.039 | ||||
Behavioral diagnosis | ||||
MCS/EMCS | VS | total | ||
Awake EEG background |
norm/mild & mod | 35 | 5 | 40 |
severe | 1 | 3 | 4 | |
total | 36 | 8 | 44 | |
*Fisher’s exact test (one tailed) p=0.015 | ||||
Behavioral diagnosis | ||||
MCS/EMCS | VS | total | ||
fMRI CF | positive | 4 | 0 | 4 |
negative | 16 | 6 | 22 | |
total | 20 | 6 | 26 | |
*Fisher’s exact test (one tailed) p=0.32 (n.s.) |