Fig. 3.
Normal locomotor activity in medial prefrontal cortext (mPFC)-specific phospholipase C-β1 (PLC-β1) knockdown mice. (A) Distance of spontaneous movement in an open-field for 1 hour was monitored at 5-minute intervals by digital video recording. (B) The small hairpin (sh)PLC-β1-injected mice show no significant difference in total distance of spontaneous locomotion compared with both scrambled sequence (shSCR)– and vehicle-injected mice (F2,28 = 0.317, p = 0.73). Data are presented as means ± standard errors of the mean (n = 12 per group).