Table 1.
Sociodemographic and clinical characteristics of study participants
| Group; mean ± SD* | ||||
|---|---|---|---|---|
|
|
||||
| Characteristic | Group I, n = 21† | Group II, n = 19‡ | Between-group differences | p value |
| Age, yr | 40.95 ± 9.6 | 38.1 ± 10.4 | t = 0.916 | 0.37 |
| Sex, male:female | 18:3 | 12:7 | χ2 = 2.707 | 0.10 |
| Duration of illness, yr | 11.4 ± 1.7 | 11.3 ± 1.8 | t = 2.941 | 0.006 |
| Education, yr | 10.7 ± 1.7 | 11.1 ± 1.9 | t = 0.205 | 0.84 |
| Premorbid intelligence | 110.7 ± 16.6 | 110.4 ± 12.5 | t = 0.052 | 0.96 |
| Y-BOCS | ||||
| Obsession | 6.7 ± 4.8 | 0.5 ± 1.6 | Z = −4.081 | < 0.001 |
| Compulsion | 5.7 ± 5.4 | 1.6 ± 2.9 | Z = −2.530 | 0.011 |
| Total | 12.4 ± 9.0 | 2.2 ± 3.9 | Z = −3.667 | < 0.001 |
| HZI | ||||
| Checking | 5.0 ± 2.9 | 2.2 ± 2.1 | Z = −3.055 | 0.002 |
| Washing | 1.5 ± 1.7 | 1.4 ± 1.5 | Z = −0.167 | 0.87 |
| Ordering | 2.6 ± 1.7 | 2.1 ± 1.4 | Z = −0.751 | 0.45 |
| Counting | 2.1 ± 2.4 | 0.3 ± 0.5 | Z = −2.741 | 0.010 |
| Obsessions | 2.2 ± 2.0 | 2.1 ± 1.5 | Z = −0.196 | 0.85 |
| Aggressive obsessions | 1.4 ± 1.9 | 0.3 ± 0.7 | Z = −2.077 | 0.08 |
| PANSS | ||||
| Positive scale | 13.4 ± 3.3 | 12.8 ± 2.9 | F = 0.220 | 0.80 |
| Negative scale | 16.8 ± 4.2 | 13.6 ± 4.7 | F = 2.842 | 0.07 |
| General psychopathology | 33.7 ± 4.9 | 32.1 ± 5.5 | F = 0.987 | 0.38 |
| Total | 63.9 ± 10.4 | 58.5 ± 11.8 | F = 1.366 | 0.27 |
| CDSS | 1.2 ± 1.5 | 1.8 ± 2.9 | F = 1.083 | 0.31 |
| General functioning | ||||
| CGI | 3.6 ± 0.8 | 3.1 ± 0.7 | χ2 = 7.742 | 0.06 |
| PSP | 67.3 ± 6.5 | 71.3 ± 7.7 | F = 2.495 | 0.10 |
CDSS = Calgary Depression Scale for Schizophrenia; CGI = Clinical Global Impression (Scale); HZI = Hamburger Zwangsinventar; PANSS = Positive and Negative Syndrome Scale; PSP = Personal and Social Performance Scale; SD = standard deviation; Y-BOCS = Yale–Brown Obsessive–Compulsive Scale.
*
Unless otherwise indicated.
†
Group I = clozapine/olanzapine.
‡
Group II = amisulpride/aripiprazole.