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. Author manuscript; available in PMC: 2015 Jul 8.
Published in final edited form as: Nature. 2014 Oct 22;517(7533):205–208. doi: 10.1038/nature13828

Figure 3. Adoptive transfer of resistance-associated intestinal bacteria following antibiotic exposure increases resistance to C. difficile infection.

Figure 3

Intestinal burden of C. difficile CFU (a) and toxin (b) 24 hours after C. difficile infection of antibiotic-exposed animals receiving adoptive transfers. Weight loss (c) and mortality (d) of animals post-infection. Correlation of adoptively-transferred bacteria engraftment with C. difficile susceptibility, (e) and microbiota biodiversity (f) pre-infection. ****P<0.0001, **P<0.01, *P<0.05, ns (not significant). Mean (f)), error bars (range (a), s.e.m. (f)).