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. Author manuscript; available in PMC: 2015 Jul 8.
Published in final edited form as: Nature. 2014 Oct 22;517(7533):205–208. doi: 10.1038/nature13828

Extended Data Figure 6. Adoptive transfer of consortia or C. scindens restores baiCD and secondary bile acid biosynthesis gene family abundance.

Extended Data Figure 6

PCR-based detection of the 7α-HSDH-encoding baiCD gene in bacterial isolates, intestinal microbiomes (feces) of animals prior to antibiotic exposure, and intestinal microbiomes (feces) of animals that, following antibiotic exposure, remained C. difficile-susceptible or recovered resistance to infection spontaneously or following adoptive transfer of bacterial isolates (a). Reconstituted abundance of the secondary bile acid biosynthesis gene family, as predicted by PICRUSt, in antibiotic-exposed animals receiving adoptive transfers (n=10 per group) (b). ***P<0.001, *P<0.05, ns (not significant); Mann-Whitney (two-tailed) (b). Center values (mean), error bars (s.e.m.).