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βTCFDN mouse islets show reduced β-cell specific gene expression and attenuated response to GLP-1 treatment. A) qPCR assessment for β-cell specific gene expression. n = 3 for both βTCFDN and control ins2-rtTA mice. B) Assessment of insulin secretion by GLP-1 treatment in isolated βTCFDN mouse islets. n = 3 for both βTCFDN and control ins2-rtTA mice.
