Table 3.
Association of (A) dominant-hand pegboard times and (B) Unified Parkinson Disease Rating Scale motor subsection part 3 (UPDRS3) scores with cumulative exposure, both unadjusted and adjusted for a learning effect. [SD=standard deviation; 95% CI=95% confidence interval.]
| A. Pegboard | Unadjusted for learning effect |
Adjusted for learning effect |
||||
|---|---|---|---|---|---|---|
| SD a | ß | 95% CI | SD | ß | 95% CI | |
| A. Pegboard | ||||||
| Cumulative exposure | −0.60 | −1.00– −0.21 | −0.68 | −1.6–0.27 | ||
| Age at baseline | 0.26 | 0.05–0.47 | 0.26 | 0.05–0.47 | ||
| Previous tests (N) | −0.08 | −1.6–1.4 | ||||
| Months since previous test | 1.22 | 0.27–1.83 | ||||
| Not first test | −3.1 | −6.4–0.20 | ||||
| Within subject | 5.8 | 5.2–6.5 | 5.8 | 5.1–6.5 | ||
| Between subject | 6.7 | 5.2–8.5 | 6.7 | 5.3–8.6 | ||
| B. UPDRS3 | ||||||
| Cumulative exposure | −0.12 | −0.21– −0.04 | −0.01 | −0.22–0.19 | ||
| Age at baseline | 0.03 | −0.02–0.08 | 0.03 | −0.02–0.08 | ||
| Previous tests (N) | −0.21 | −0.55–0.14 | ||||
| Months since previous test | 0.061 | −0.12–0.27 | ||||
| Not first test | −0.15 | −0.92–0.62 | ||||
| Within subject | 1.3 | 1.2–1.5 | 1.3 | 1.2–1.5 | ||
| Between subject | 1.6 | 1.3–2.0 | 1.6 | 1.3–2.0 | ||
a
From mixed effects restricted maximum likelihood (REML) regression.