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. 2015 Feb 21;15:28. doi: 10.1186/s12906-015-0548-0

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© Wang et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The myocardial concentration of PPARα, RXR, NR2C2 and P450. The results showed that the levels of PPARα and RXR decreased compared with sham-operated group. The level of NR2C2 increased significantly. A reduction level of P450 was observed in the model group. In DQP group, PPARα-RXR pathway was up-regulated, together with decreased level of NR2C2. P450 level was also increased. Pravastatin had similar efficacy on all these indicators as DQP, except for PPARα.*P < 0.05, **P < 0.01. Levels in the model group were used as reference to calculate P values.