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. 2014 Dec 1;24(7):1869–1882. doi: 10.1093/hmg/ddu604

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© The Author 2014. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Muscle involved in ET opening is hypoplastic in adult Df1/+ mice. (A and B) Trichrome-stained frontal sections of the (A) nasopharynx (NP) and frontal portion of the ET (arrow) showing the levator veli palatini (mLVP, yellow) and Palatopharyngeus muscle (mPP, purple) inserting into the soft palate (SP) in 11.5-week-old control littermates. (B) Df1/+ mice show a reduction in muscle size. (C) Measurements of the mLVP (yellow) volume from histological frontal sections show that muscles in adult Df1/+ animals (n = 8) are significantly smaller compared with those of control littermates (n = 2; P < 0.0444). Statistical analysis was performed using non-parametric Mann–Whitney test. Scale bars: A and B, 200 µm.