Table 1.
GAL4 line | Tissue | Phenotype (co-expression of α-syn and mutant Htt) |
---|---|---|
TH-GAL4 | Dopaminergic neurons | Co-localization, interaction and co-aggregation of α-syn and Htt |
nSyb-GAL4 | Nervous system | Impairment of motor abilities and reduced life span |
sGMR-GAL4 | Eye | Co-localization, co-aggregation and retinal degeneration |
Rh1-GAL4 | Photoreceptors R1-R6 | Premature degeneration of the photoreceptors |