FKBP65 accumulates in ER-related vesicles in OI-mutant cells. Immunofluorescence of FKBP65 (green) and cell compartments (red): PDI for ER (A–C), Golgin97 for Golgi apparatus (D–F) and ERGIC53 for ER–Golgi intermediate compartment (G–I). Control (A, D and G), HSP47M237T/M237T (B, E and H) and FKBP10−/− cells (C, F and I). White arrows identify vesicles accumulating FKBP65. Bars represent 10 µm.