Table III.
Full Asthma Prediction Rule models, penalized odds ratios for associations of predictor variables with primary outcome of need for hospitalization and secondary outcome of decision of the clinical team for hospitalization in 928 participants aged 5 - 17 years with asthma exacerbations
| Need for hospitalization |
Hospitalization decision of the clinical team |
|
|---|---|---|
| Age (Years, change from 6.9 to 11 years) | 1.4 (1.1 – 1.9) | 1.3 (1.0 - 1.8) |
| BMI (Kg/M2) change from 15.6 to 22) | 1.0 (0.8 – 1.3) | 0.9 (0.7- 1.2) |
| SpO2 (%, change from 98 to 94%) | 2.4 (1.9 – 3.0) | 3.9 (3.0 - 5.0) |
| Gender (Female:Male) | 1.3 (0.9 – 1.8) | 1.1 (0.8 - 1.6) |
| Race (white:other) | 1.1 (0.8 – 1.6) | 0.9 (0.7 - 1.3) |
| Daytime asthma sx > 2/wk | 1.1 (0.7 -1.6) | 1.1 (0.7 - 1.7) |
| Nocturnal asthma sx or awakening | 1.0 (0.7 – 1.4) | 0.9 (0.6 - 1.4) |
| Limitation of activity due to asthma | 1.1 (0.8 – 1.6) | 1.1 (0.8 - 1.6) |
| Need for albuterol > 2/wk | 1.1 (0.8 – 1.7) | 1.0 (0.7 - 1.6) |
| Asthma exacerbation in past year | 1.1 (0.8 – 1.6) | 1.1 (0.8 - 1.6) |
| Sternomastoid-suprasternal retractions | 1.0 (0.7 – 1.5) | 1.1 (0.7 - 1.7) |
| Intercostal retractions | 1.4 (0.9 – 2.0) | 1.6 (1.0 - 2.4) |
| Subcostal retractions | 1.0 (0.7 – 1.4) | 1.0 (0.7 - 1.5) |
| Inspiratory:Expiratory ratio (1:2 vs. 1:1) | 1.0 (0.7 – 1.5) | 1.3 (0.8 – 2.0) |
| Inspiratory:Expiratory ratio (≤ 1:3 vs. 1:1) | 1.9 (1.1 – 3.1) | 2.0 (1.1 - 3.7) |
| Wheezing (expiratory:none) | 1.2 (0.8 – 1.90) | 1.4 (0.8 - 2.5) |
| Wheezing (inspiratory + expiratory vs. none) | 1.23 (0.8 – 2.0) | 2.1 (1.2 - 3.7) |
Age and BMI included as flexible smooth variables using restricted cubic splines.
BMI = body mass index; SpO2 = oxygen saturation on room air Values are odd ratios (95% CI) estimated using penalized maximum likelihood logistic regression.