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. 2015 Mar 10;10(3):e0116504. doi: 10.1371/journal.pone.0116504

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© 2015 Boe et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 1 — Lung tissue sections from (A) WT, (B) WT + L-NAME, (C) WT + L-NAME + TM5441, and (D) PAI-1-/- + L-NAME demonstrate that L-NAME causes significant alveolar destruction and that PAI-1 inhibition is partially protective against this. (E) Mean linear intercept quantifications. *P = 0.0002, #P = 0.04, $P = 0.009. Data are mean ± SD. n = 11–13.