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. 2015 Mar 10;10(3):e0116504. doi: 10.1371/journal.pone.0116504

Fig 2. Effects of L-NAME on lung functional dynamics.

Fig 2

Measurements for (A) compliance, (B) static compliance, (C) elastance, and (D) static elastance demonstrate that L-NAME-treated lungs have the functional characteristics of emphysema. Both genetic and pharmacologic inhibition of PAI-1 protected mice from lung dysfunction. (A) and (C) *P = 0.002, #P = 0.02, $P = 6.3x10-6. (B) and (D) *P = 0.004, #P = 0.01. Data are mean ± SD. n = 6–7.