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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Cancer Prev Res (Phila). 2015 Feb 13;8(3):231–239. doi: 10.1158/1940-6207.CAPR-14-0181-T

Figure 2. Effects of Metformin on the Development of Mammary Carcinomas in MMTV-Neu/P53KO mice.

Figure 2

Weanling mice were characterized for the presence both the MMTV-Neu transgene and the KO of one copy of the tumor suppressor gene p53. Mice were placed on control diet or diet containing 1500 mg/kg metformin at 60 days of age. Metformin did not significantly increase survival (P<.05) (A), and also did not impact incidence, multiplicity, (B), or cancer weight (C).