Table 2.
TLR mRNA expression as predictor of HPV16 clearance
TLR | Unadjusted HR1 | p value | Adjusted2 HR1 | p value |
---|---|---|---|---|
TLR2 | 1.010 (0.942–1.083) | 0.779 | 1.010 (0.942–1.084) | 0.776 |
TLR3 | 1.057 (1.005–1.112) | 0.032 | 1.060 (1.007–1.117) | 0.026 |
TLR7 | 1.105 (1.015–1.204) | 0.022 | 1.110 (1.017–1.212) | 0.020 |
TLR8 | 1.109 (0.994–1.195) | 0.067 | 1.091 (0.994–1.197) | 0.065 |
TLR9 | 1.060 (0.980–1.148) | 0.148 | 1.062 (0.980–1.150) | 0.142 |
Cox proportional hazard ratio (95% confidence interval) representing incremental likelihood of clearance for each additional 2-fold difference in relative TLR expression.
Adjusted for tobacco smoking and oral contraceptive pill use.
Abbreviation: HR, hazard ratio.