Table 1.
Maternal characteristics of the 2nd pregnancy and obstetric outcomes of the 1st pregnancy by preeclampsia status among nulliparous women in the NICHD Consecutive Pregnancy Study, 2002–2010
| No preeclampsia in 1st or 2nd pregnancyc N=24,980 |
Preeclampsia in 1st pregnancy onlyd N=1,137 |
Preeclampsia in 2nd pregnancy onlye N=341 |
Recurrent preeclampsia N=155 |
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| Maternal characteristics of the 2nd pregnancy/Obstetric outcomes of the 1st pregnancy
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| Maternal age (y)a | 26.2 (4.1) | 26.3 (4.3) | 26.5 (4.1) | 26.2 (4.7) |
| Non-Hispanic Whiteb | 21802 (87) | 1007 (89) | 298 (88) | 125 (81) |
| Married | 22278 (89) | 1010 (89) | 299 (88) | 138 (89) |
| Private insurance | 18187 (73) | 833 (73) | 238 (70) | 100 (65) |
| Alcohol during pregnancy | 405 (2) | 9 (1) | 8 (2) | 3 (2) |
| Smoke during pregnancy | 710 (3) | 32 (3) | 12 (4) | 6 (4) |
| Interpregnancy interval (months) | ||||
| 0–5 | 1423 (6) | 68 (6) | 24 (7) | 18 (12) |
| 6–11 | 4602 (18) | 196 (17) | 49 (14) | 24 (16) |
| 12–17 | 6583 (26) | 304 (27) | 88 (26) | 31 (20) |
| 18–23 | 5477 (22) | 238 (21) | 55 (16) | 31 (20) |
| ≥24 | 6895 (28) | 331 (29) | 125 (37) | 51 (33) |
| 1st & 2nd prepregnancy weight difference (kg) | ||||
| <−2 kg | 4876 (20) | 235 (21) | 51 (15) | 31 (21) |
| −2 to 2 kg | 8571 (35) | 325 (29) | 86 (26) | 42 (28) |
| >2 kg | 10813 (45) | 543 (49) | 195 (59) | 77 (51) |
| Pre-pregnancy BMI (kg/m2)a | 24.5 (5) | 26.9 (6) | 27.9 (7) | 27.3 (6) |
| Pre-pregnancy BMI (kg/m2) | ||||
| Underweight [<18.5] | 1378 (6) | 25 (2) | 5 (1) | 1 (1) |
| Normal [18.5–24.9] | 14435 (59) | 514 (46) | 139 (41) | 55 (36) |
| Overweight [25.0–29.9] | 5361 (22) | 302 (27) | 88 (26) | 53 (35) |
| Obese class I [30.0–34.9] | 2138 (9) | 147 (13) | 49 (14) | 28 (19) |
| Obese class II & III [>35.0] | 1321 (5) | 136 (12) | 58 (17) | 14 (9) |
| Gestational weight gain (kg)a | 13.4 (6) | 13.8 (6) | 13.9 (7) | 14.3 (7) |
| Thyroid disease | 1253 (5) | 68 (6) | 17 (5) | 9 (6) |
| Asthma | 2078 (8) | 105 (9) | 24 (7) | 15 (10) |
| Depression | 2496 (10) | 141 (12) | 38 (11) | 20 (13) |
| Gestational diabetes | 683 (3) | 58 (5) | 11 (3) | 15 (10) |
| Preexisting diabetes | 152 (1) | 10 (1) | 3 (1) | 2 (1) |
| Antihypertensive medication | 15 (0) | 3 (0) | 25 (7) | 19 (12) |
| Induction of labor | 9157 (37) | 437 (38) | 235 (69) | 72 (46) |
| Cesarean delivery | 4408 (18) | 369 (32) | 92 (27) | 76 (49) |
| Cesarean for failing to progress | 518 (2) | 37 (3) | 8 (2) | 11 (7) |
| SGA in 1st pregnancy | 1017 (4) | 92 (8) | 19 (6) | 8 (5) |
| Preterm <34 week in 1st pregnancy | 393 (2) | 80 (7) | 15 (4) | 25 (16) |
Abbreviations: BMI: body mass index; SGA: small for gestational age.
Data were missing for: race/ethnicity: 30; married: 2; alcohol: 67; smoke: 18; prepregnancy weight difference: 768; prepregnancy BMI: 366; gestational weight gain: 397; gestational diabetes/preexisting diabetes: 13; cesarean delivery: 1; SGA in previous pregnancy: 26.
All figures are N (%) unless otherwise stated.
Mean (SD).
Non-whites included: non-Hispanic Black (n=110, 0.4%); Hispanic (n=2554, 10%); Asian/Pacific Islander (n=592, 2%); Other race (n=95, 0.4%).
Includes normotensive women and women with gestational hypertension during the 1st and/or 2nd pregnancy.
Includes women with preeclampsia/eclampsia in their 1st pregnancy who were either normotensive or had gestational hypertension in their 2nd pregnancy.
Includes women with preeclampsia/eclampsia in their 2nd pregnancy who were either normotensive or had gestational hypertension in their 1st pregnancy.