Figure 1.

Blood vessel development in early postimplantation mouse embryos. (A) At E8.5, angioblasts and endothelial cells migrate medially and ventrally from lateral plate mesoderm and somites, and laterally from somites. (B) At E9.5, angiogenic sprouting from the perineural vascular plexus (pnvp) vascularizes the neural tube. Embryo silhouettes show pattern of trunk and intersomitic vessels in red (heart and head vessels are excluded); maroon arrows indicate migratory streams or direction of sprouting; black line denotes pnvp; da, dorsal aorta; lpm, lateral plate mesoderm; nc, notochord; nt, neural tube; som, somite; A, anterior; P, posterior; D, dorsal; V, ventral.