Table 1.
Characteristics of human urine samples tested for miRNA expression
| A. Arsenic exposed and unexposed normal urine samples | ||||
|---|---|---|---|---|
| Characteristics | Arsenic Exposed (n=110) |
Arsenic unexposed | ||
| Smokers (n=11) | Non-smokers (n=46) | Total (n=67*) | ||
| Age | ||||
| Mean | 36.8 | 59.4 | 68.2 | 66.5 |
| Range | 20–65 | 50–73 | 39–94 | 39–94 |
| Gender | ||||
| Male | 54 | 8 | 37 | 45 |
| Female | 56 | 3 | 9 | 12 |
| Smoking history | ||||
| Never | Not available | N/A | N/A | 46 |
| 0–20pack years | Not available | 5 | N/A | 5 |
| >20–35 pack years | Not available | 1 | N/A | 1 |
| >35 pack years | Not available | 5 | N/A | 5 |
| Unknown | Not available | N/A | N/A | 10 |
| Water arsenic, µg/L | ||||
| <10 | 28 | N/A | N/A | N/A |
| 10–50 | 22 | N/A | N/A | N/A |
| >50 | 21 | N/A | N/A | N/A |
| Unknown | 39 | N/A | N/A | N/A |
| Creatinine adjusted urine arsenic, µg/g | ||||
| <100 | 35 | N/A | N/A | N/A |
| 100–200 | 38 | N/A | N/A | N/A |
| >200 | 37 | N/A | N/A | N/A |
| B. UC and Arsenic unexposed normal urine samples | ||||
|---|---|---|---|---|
| Characteristics | Cancer (n=32) |
Arsenic unexposed | ||
| Smokers (n=11) | Non-smokers (n=46) | Total (n=67*) | ||
| Age | ||||
| Mean | 65.4 | 59.4 | 68.2 | 66.5 |
| Range | 36–84 | 50–73 | 39–94 | 39–94 |
| Gender | ||||
| Male | 26 | 8 | 37 | 45 |
| Female | 6 | 3 | 9 | 12 |
| Stage | ||||
| CIS | 7 | N/A | N/A | N/A |
| pTa | 16 | N/A | N/A | N/A |
| T1 | 5 | N/A | N/A | N/A |
| ≥pT2 | 4 | N/A | N/A | N/A |
*
Included 10 unexposed samples with unknown smoking history, N/A: not applicable