Fig 3. Leptin signaling is required for adaptive changes in energy intake in response to a thermal challenge.
(A) Photoperiod-averaged energy intake profiles and (B) the relationship between energy intake and ambient temperature in adult male ob/ob mice and wild-type (WT) littermate controls housed under different ambient temperature conditions (n = 8/group). Mean±SEM. ***p<0.001, *p<0.05.