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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Eur J Pharm Biopharm. 2014 Dec 13;89:271–279. doi: 10.1016/j.ejpb.2014.12.010

Figure 7.

Figure 7

Top-panels: HDP-CDV treated eye (HDP-CDV Tx) presented relatively normal fundus (left image); histology revealed only mild vitritis with inflammatory cells seen along the retina surface (right image). Mid-panels: CDV treated eye (CDV Tx) showed hazy vitreous with extensive retinal detachment (RD) (left image); histology revealed disorganized retina (R) layers with much more inflammatory cells along the retina surface (right image). Both RPE (arrowheads) and choroid (CH) are swelling. Bottom-panels: Dextrose injected eye revealed distorted optic nerve (ON) and shortened right side medullary ray (left image); histology showed no recognizable retinal layers and RPE was barely recognizable (arrowheads) with inflammatory cells packed in both retina area (R) and in Choroid (CH).