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. 2015 Mar 7;14:22. doi: 10.1186/s12937-015-0010-7

Figure 1.

Figure 1

Simplified two-dimensional schematics of immunoglobulin G (IgG). A. Schematic showing the variable and constant regions of the IgG molecule for the heavy (CHx) and light chains (CL); B. Schematic of the antigen binding fragments (Fab1,2) and the fragment crystallizable region (Fc) of the IgG molecule; C. Schematic portraying intra- and interchain disulfide bonds as well as glycosylation of the Fab, Fc regions, and paratope antigen binding regions of the IgG molecule.