Table 1.

Information provided to participants on risk stratification and risk management options

Opinions on a risk prediction program using risk stratification approach

Risk stratification means that women can be grouped based on their likelihood of getting ovarian cancer. Women can be described as having a low, intermediate or high risk. The level of risk is based on a woman’s genetic risk and other risk factors. Identifying genetic risk involves having a blood test. Identifying other risk factors would involve filling in questionnaires about cancer family history, background and health information. Scientists can then put all of this information together and estimate whether a women is at low, intermediate or high risk. It is estimated that 50–60 % of women will be at low risk, 30–45 % at intermediate risk, and 4–7 % at high risk

Opinions on possible risk management options

Depending on a woman’s risk level (low, intermediate or high), she would receive different levels of risk management for ovarian cancer. Women at low risk would receive information telling them that they are at low risk and that they do not need further monitoring. This information would also let low-risk individuals know about symptoms of ovarian cancer. Women at intermediate risk would receive screening every year (screening involves a blood test to check for levels of the biomarker CA-125 followed by transvaginal ultrasound). Those at high risk would be screened every 4 months. High-risk women may also be referred to a specialist to discuss risk-reducing surgery