Table 2.
Correlation coefficients of 1-year changes
| Variable 1 | Variable 2 | Whole group r ( N; P ) | NGT group r ( N; P ) | T2D group r ( N; P ) |
|---|---|---|---|---|
| IL-6 | BMI | 0.16(20; 0.49) | 0.01(9; 0.98) | 0.28(11; 0.40) |
| HOMA-IR | 0.19(20; 0.19) | −0.07(9; 0.88) | 0.21(11; 0.52) | |
| HbA1c | 0.47(19; 0.04) | 0.02(8; 0.98) | 0.82(11; 0.002) | |
| TGF-β | 0.65(20; 0.002) | 0.70(9; 0.04) | 0.71(11; 0.01) | |
| IL-8 | BMI | 0.02(20; 0.92) | −0.13(9; 0.73) | 0.03(11; 0.94) |
| HOMA-IR | 0.06(20; 0.81) | −0.20(9; 0.61) | 0.37(11; 0.26) | |
| HbA1c | −0.14(19; 0.57) | 0.15(8; 0.73) | 0.45(11; 0.17) | |
| GLP-1 | 0.59(20; 0.007) | 0.80(9; 0.01) | 0.54(11; 0.09) | |
| Adiponectin | 0.35(20; 0.12) | 0.67(9; 0.05) | 0.27(11; 0.42) | |
| TGF-β | BMI | 0.28(24; 0.19) | 0.37(11; 0.26) | 0.25(13; 0.42) |
| HOMA-IR | 0.05(24; 0.81) | −0.10(11; 0.77) | 0.19(13; 0.54) | |
| HbA1c | 0.25(23; 0.26) | 0.07(10; 0.84) | 0.64(13; 0.02) | |
| Adiponectin | BMI | −0.40(21; 0.07) | −0.28(9; 0.11) | −0.42(12; 0.17) |
| HOMA-IR | −0.28(21; 0.21) | −0.57(9; 0.11) | −0.19(12; 0.56) | |
| HbA1c | −0.06(20; 0.79) | −0.07(8; 0.86) | −0.32(12; 0.31) | |
| GLP-1 | 0.47(21; 0.03) | 0.87(9; 0.003) | 0.16(12; 0.62) | |
| Leptin | −0.58(21; 0.01) | −0.68(9; 0.04) | −0.36(12; 0.26) | |
| Leptin | BMI | 0.65(21; 0.002) | 0.75(9; 0.02) | 0.56(12; 0.06) |
| HOMA-IR | 0.36(21; 0.11) | 0.72(9; 0.03) | 0.45(12; 0.14) | |
| HbA1c | −0.14(20; 0.55) | 0.41(8; 0.31) | −0.08(12; 0.19) | |
| Insulin | 0.51(21; 0.02) | 0.28(9; 0.46) | 0.41(12; 0.81) |
Clinically relevant significant and non-significant correlation coefficients in the whole study population and in T2D subjects and NGT subjects. Data are presented as r: correlation coefficient of correlation, and the sample size and P-value in parentheses. NGT, normal glucose tolerant subjects; T2D, type 2 diabetes subjects; BMI, body mass index; HbA1c, glycated hemoglobin; HOMA-IR, homeostasis model assessment of insulin resistance. Data are analyzed by Spearman correlation test, P < 0.05.