Table 6.
Formula number | Evaluation parameters | |||
---|---|---|---|---|
Weight variation (IP) | Friability (%) | Hardness* (Kg/cm2) ± S.D | Disintegration time** (Sec) ± S.D | |
F1 | Passed | 0.1 | 2.2 ± 0.28 | 60 ± 1.78 |
F2 | Passed | 0.2 | 1.8 ± 0.28 | 47 ± 2.45 |
F3 | Passed | 0.5 | 2.0 ± 0.00 | 69 ± 2.89 |
F4 | Passed | 0.3 | 3.2 ± 0.76 | 83 ± 2.40 |
F5 | Passed | 0.3 | 1.6 ± 0.50 | 90 ± 5.16 |
F6 | Passed | 0.8 | 2.5 ± 0.50 | 120 ± 5.77 |
F7 | Passed | 0.8 | 2.0 ± 0.00 | 145 ± 5.43 |
F8 | Passed | 0.1 | 1.5 ± 0.50 | 38 ± 4.34 |
F9 | Passed | 0.1 | 1.5 ± 0.28 | 47 ± 2.34 |
F10 | Passed | 0.2 | 1.5 ± 0.28 | 62 ± 3.10 |
F11 | Passed | 0.1 | 1.8 ± 0.28 | 75 ± 1.32 |
F12 | Passed | 0.1 | 1.5 ± 0.28 | 82 ± 2.08 |
F13 | Passed | 0.1 | 1.8 ± 0.28 | 94 ± 3.67 |
F14 | Passed | 0.1 | 1.8 ± 0.28 | 110 ± 2.78 |
*Average of three determinations.
**Average of six determinations.