Table 5. Gene and pathway—level associations.

Gene / Pathway	Trait	p
Single genes
TLR7	HE_any a	0.06194
TLR3	HE2 b	0.02198
Pathways
TLR3-TRIF	HE2	0.0348
TLR7-TLR8-MyD88	HE_any	0.0458
TLR3-TRIF	ME3 c	0.0176
TLR7-MyD88	HE_any	0.0701
TLR8-MyD88	HE_any	0.0394
IL6-IL6R	Nonspec3 d	0.06499

All p < 0.10 shown

^a HE-any = Hemorrhagic fever symptoms—any

^b HE2 = Hemorrhagic fever—2 or more symptoms

^c ME3 = Meningoencephalitis—3 or more symptoms

^d nonspec3 = RVFV non-specific—3 or more symptoms