Table 1.
Basic characteristics of all subjects included in this study.
| Variable | Chronic HCV | Cirrhosis+HCC | Control | P value |
|---|---|---|---|---|
| Age (yrs.)¶ | 48.00 (36.00–57.00) | 57.00 (48.00–63.00) | 29.00 (24.00–36.00) | <0.000§ |
| Sex | ||||
| Male count (%) | 274 (50.5%) | 94 (51.4%) | 568 (94.7%) | <0.000ϕ |
| Female count (%) | 269 (49.5%) | 89 (48.6%) | 32 (5.3%) | |
| BMI¶ | 31.88 (26.53–71.43) | 28.72 (24.57–34.13) | 0.014§ | |
| Platelet count (109/L)¶ | 216.00 (169.00–284.50) | 148.00 (102.50–200.50) | <0.000§ | |
| Bil (umol/L)* | 13.21 ± 26.18 | 25.07 ± 73.34 | <0.000ψ | |
| ALT (IU/L)* | 74.53 ± 66.9 | 83.66 ± 62.47 | 0.766ψ | |
| AST (IU/L)* | 45.07 ± 40.299 | 75.16 ± 57.16 | <0.000ψ | |
| AFP (ug/L)* | 6.36 ± 22.03 | 15.97 ± 27.14 | <0.000ψ | |
| ALP (IU/L)* | 106.30 ± 53.07 | 122.65 ± 76.77 | 0.004ψ | |
| Creatinine (umol/L)* | 110 ± 151.31 | 97.72 ± 127.30 | 0.074ψ | |
| HCV load IU/mL (log10)¶ | 5.80 (4.788–6.41) | 6.025 (5.49–6.44) | 0.511§ | |
| HCV genotypes | ||||
| 4 (357) | 249 (70%) | 108 (30%) | <0.0001 | |
| 1 (148) | 115 (77.7%) | 33 (22.3%) | ||
| Others¶¶ (173) | 154 (89%) | 19 (11%) |
BMI: body mass index; Bil: bilirubin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; AFP: α-fetoprotein, ALP: alkaline phosphatase. *Values are expressed as mean ± SD, ¶values are expressed as median-interquartile range (25th–75th), ¶¶includes genotypes 2, 3, and untypable genotypes. §Nonparametric tests, ϕChi-squared tests, and ψindependent t-tests.