Table 3.
Comparison of patient and tumor characteristics in cases with concordance or discrepancies of histology and FISH.
| Histological diagnosis | MDM2 amplified | Total | Sex of patients | Median age (years) | Median size of tumor (cm) | Classical sites for WDL/DDL (intra-abdominal or inguinal) | Review cases | Core biopsies | Resection specimens |
|---|---|---|---|---|---|---|---|---|---|
| Benign (definite/provisional) | − | 126 | 84 M : 43 F | 50.5 | 9 | 40 (31.5%) | 60 (47.2%) | 16 (21.6%) | 58 (78.4%) |
| + (i.e., discrepant with histology) |
15 | 8 M : 7 F | 59 | 15 | 8 (53.3%) | 5 (33.3%) | 5 (45.5%) | 6 (54.5%) | |
|
| |||||||||
| Liposarcoma (definite/provisional) | − (i.e., discrepant with histology) |
15 | 5 M : 12 F | 64 | 13.5 | 10 (66.7%) | 2 (13.3%) | 5 (38.5%) | 8 (61.5%) |
| + | 142 | 92 M : 50 F | 63 | 18 | 113 (79.6%) | 27 (19.0%) | 31 (29.2%) | 75 (70.8%) | |