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. 2015 Mar 10;11(3):e1005076. doi: 10.1371/journal.pgen.1005076

Table 6. TDT analysis stratified by maternal specific sensitization.

Transmission Disequilibrium Test (TDT) Allelic test in children d
Group n a T / U b OR c P Mut freq OR (P)
+Mat_sens 253 97 / 65 1.49 0.04 0.11 1
−Mat_sens 311 169 / 68 2.49 5.3 x10−8 0.16 1.48 (0.005)

a Number of families.

b Number of transmitted (T) and un-transmitted (U) alleles. Allele counts are referred to the combined FLG mutations.

c Odds ratio calculated as the ratio of transmitted versus un-transmitted alleles.

d Comparison of allelic frequency between AD-affected children of the −Mat_sens versus the +Mat_sens families.