Table 2.

Association between XRCC1 and XRCC3 genotype profiles and risk for chronic gastritis (CG) and gastric cancer (GC)

XRCC1		XRCC3	Groups
Codon 194	Codon 399	Codon 241	CG	GC	OR (95%CI) P	CG	C1	OR (95%CI) P	GC	C2	OR (95%CI) P
All wide-type genotypes
Arg	Arg	Thr	33	32	1.0 (reference)	33	34	1.0 (reference)	32	23	1.0 (reference)
One variant polymorphism
Trp	Arg	Thr	5	8	0.6 (0.17-2.04) 0.5469	5	6	1.2 (0.32-4.16) 1.0000	8	6	1.1 (0.32-3.44) 1.0000
Arg	Gln	Thr	51	38	1.4 (0.68-2.50) 0.5124	51	42	0.8 (0.42-1.51) 0.5234	38	34	1.2 (0.61-2.56) 0.5918
Arg	Arg	Met	50	27	2.0 (0.91-3.57) 0.1237	50	49	1.0 (0.51-1.75) 1.0000	27	34	2,0 (0.83-3.70) 0.1426
Two variant polymorphisms
Trp	Gln	Thr	3	5	0.6 (0.13-2.63) 0.7106	3	2	0.6 (0.1-4.16) 1.0000	5	4	1.1 (0.16-4.54) 1.0000
Arg	Gln	Met	43	43	1.0 (0.50-1.85) 1.0000	43	58	1.4 (0.69-2.43) 0.4309	43	39	1.2 (0.63-2.50) 0.5389
Trp	Arg	Met	10	6	1.6 (0.52-5.00) 0.5771	10	6	0.6 (0.19-1.78) 0.4106	6	7	1.6 (0.48-5.55) 0.5999
Three variant polymorphisms
Trp	Gln	Met	8	1	8.3 (0.91-100) 0.0372	8	5	0.6 (0.17-2.04) 0.5400	1	3	5.0 (0.40-50.0) 0.3113