Table 1.
Egyptian |
Japanese |
|||||
HCC (+) | HCC (–) | P | HCC (+) | HCC (–) | P | |
n = 65 | n = 106 | n = 45 | n = 128 | |||
Mean age (SD, yr) | 57±11b | 47±9 | <0.001 | 66±10b | 63±10 | NS |
Age <50 yr | 16 (25)d | 65 (61) | <0.001 | 3 (7)d | 17 (13) | NS |
Male | 50 (77) | 82 (77) | NS | 38 (84) | 87 (68) | 0.024 |
Liver disease | ||||||
Viral | 61 (94) | 96 (91) | 44 (98) | 107 (84) | ||
HCV-related | 59 (91) | 92 (87) | NS | 36 (80) | 81 (63) | 0.031 |
HBV-related | 2 (3)1 | 4 (4) | NS | 8 (18)1 | 28 (22) | NS |
Non-viral | 4 (6) | 10 (9) | NS | 1 (2) | 20 (16) | 0.010 |
Cirrhosis | 46 (71) | 45 (42) | <0.001 | 40 (89) | 40 (31) | <0.001 |
Child’s C | 25 (38)f | 17 (16) | 0.001 | 4 (9)f | 1 (1) | 0.017 |
Mean±(SD) | ||||||
ALT (IU/L) | 73±95 | 66±45 | 0.08 | 55±35 | 50±39 | NS |
Serum Albumin (g/L) | 3.0±0.7 | 3.0±0.5 | NS | 3.6 ±0.5 | 4.2±0.4 | <0.001 |
Platelet count×1 000/mL3 | 186±107h | 89±53 | 0.001 | 130±51h | 170±71 | <0.001 |
AFP >10 ng/mL (+) | 64 (99) | 28 (26) | <0.001 | 30 (67) | 23 (18) | <0.001 |
PIVIKA>40 mAU/L (+) | 51 (79) | 38 (36) | <0.001 | 16 (36) | 27 (21) | 0.047 |
P<0.001,
P<0.001,
P<0.001,
P<0.001 vs Japannese,
P = 0.001.