Table 2.
Cytokine | HCC (n = 33) | CLD(n = 20) | ASC(n = 20) | NC(n = 20) | P |
IL-2 | 3.07±0.01 | 3.07±0.005 | 3.07±0.009 | 3.08±0.004 | >0.05 |
Cut-off=3.087 pg/mL | |||||
Number of positive cases | 1 (3%) | 0 | 6 (30%) | 0 | |
IL-2R | 16.67±5.44 | 16.28±5.28 | 3.42±1.85 | 1.39±1.09 | <0.001 |
Cut-off=3.5 ng/mL | |||||
Number of positive cases | 30 (91%) | 16 (80%) | 9 (45%) | 1 (5%) | |
IL-6 | 4.71±2.49 | 5.2±1.68 | 6.4±1.9 | 4.82±2.62 | 0.032 |
Cut-off=10.06 ng/mL | |||||
Number of positive cases | 1 (3%) | 0 | 1 (5%) | 1 (5%) | |
IL-6R | 56.48±17.97 | 54.47±16.72 | 54.13±16.35 | 19.62±5.52 | <0.001 |
Cut-off=30.65 ng/mL | |||||
Number of positive cases | 29 (88%) | 19 (95%) | 17 (85%) | 0 | |
IL-10 | 9±26.07 | 6.59±7.57 | 3.96±2.24 | 3.13±0.79 | >0.05 |
Cut-off=4.71 pg/mL | |||||
Number of positive cases | 9 (31%) | 8 (40%) | 3 (15%) | 0 | |
TNF-α | 4.77±3.2 | 5.53±1.9 | 811±5.8 | 58±196 | <0.001 |
Cut-off=17.2 ng/mL | |||||
Number of positive cases | 0 | 0 | 20 (100%) | 1 (5%) | |
TNF-α RI | 1.27±0.98 | 1.87±1.50 | 0.56±0.23 | 0.29±0.16 | <0.001 |
Cut-off=0.599 ng/mL | |||||
Number of positive cases | 24 (72%) | 16 (80%) | 7 (35%) | 1 (5%) | |
TNF-α RII | 7.89±3.57 | 9.16±4.26 | 3.42±1.72 | 2.17±1.29 | <0.001 |
Cut-off=4.74 ng/mL | |||||
Number of positive cases | 25 (81%) | 17 (85%) | 4 (20%) | 0 |
1Cut-off=mean±2 SD of non-cancer controls. P<0.05 difference is statistically significant.