Table 1.
Skp2 protein expression in human gastric tissues
| frequency(%) | Specimens |
Skp2 labeling frequency(%) |
|
| Tissue | (n) | Median | Mean±SE |
| Normal gastric mucosa | 5 | 0.001 | 0.47±0.19 |
| Chronic superficial gastritis | 10 | 0.002 | 0.53±0.13 |
| Intestinal metaplasia | 30 | 12.003 | 12.68±0.86 |
| Dysplasia | 30 | 19.004 | 16.74±0.82 |
| Primary gastric carcinoma | 138 | 29.005 | 31.34±2.17 |
| Adjacent mucosa | 138 | 16.006 | 19.32±1.22 |
| Metastasis tumor tissue in lymph node | 102 | 39.507 | 39.76±2.00 |
1,2 ,3 ,4Frequency was significantly higher than in normal gastric tissue and chronic superficial gastritis (P = 0.000,all the same; Mann-Whitney U test). 2Frequency was significantly higher than in intestinal metaplasia (P = 0.000; Mann-Whitney U test). 3Frequency was significantly higher than in intestinal metaplasia and dysplasia, (P = 0.000,all the same; Mann-Whitney U test). 5Frequency was Significantly higher than in primary tumors (P = 0.037; Mann-Whitney U test).