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. 2015 Apr 1;38(4):545–557. doi: 10.5665/sleep.4568

Figure 4.

Figure 4

Effect of sleep fragmentation (SF) exposures during late gestation on macrophage gene expression (F4/80 and CD11b) in adipose tissue depots (VWAT and SCAT) in 20-week-old offspring. (A1,B1) Gene expression in males. (A2,B2) Gene expression in female offspring. Increased expression of macrophage related genes emerged in SF versus sleep control (P < 0.01). However, no significant differences between male and female offspring mice occurred. Data were normalized to 18S mRNA level. The results are shown as the mean ± standard error (n = 6–8 for each experimental condition). mRNA, messenger RNA; SCAT, subcutaneous adipose tissue; SCOF, sleep control female mice; SCOM, sleep control male mice; SFOF, sleep fragmented female mice; SFOM, sleep fragmented male mice; VWAT, visceral white adipose tissue.