Table 4.
Summary of estimates of risk and heterogeneity in overall and sub-group analysis
| Subgroup | Numbers ofstudies | Summary ORor RR (95% CI) | Measure of heterogeneity | Analysis | ||
|---|---|---|---|---|---|---|
| Q-value | P value | I2 | Model | |||
| Study design | ||||||
| Cohort studies | 9 | 1.23 (0.91, 1.67) | 69.63 | 0.0001 | 0.89 | RE |
| Case control studiesA | 4 | 1.30 (1.09, 1.56) | 9.56 | 0.02 | 0.69 | RE |
| Cohort studies | ||||||
| Air dioxin-related toxicantsexposure and adversepregnancy outcome | 4 | 0.99 (0.85, 1.16) | 4.17 | 0.24 | 0.28 | FE |
| Food dioxin-related toxicantsexposure and | ||||||
| Spontaneous abortion | 2 | 1.05 (0.80, 1.37) | 1.30 | 0.25 | 0.23 | RE |
| Low birth weight | 2 | 1.55 (1.24, 1.94) | 0.41 | 0.52 | 0 | RE |
| Case control studies | ||||||
| Maternal solid contaminantsdioxin exposure and birth defects | 3 | 1.24 (1.19, 1.29) | 1.52 | 0.47 | 0 | FE |