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. 2015 Feb 7;8(4):351–366. doi: 10.22074/ijfs.2015.4174

Table 4.

Summary of estimates of risk and heterogeneity in overall and sub-group analysis


Subgroup Numbers ofstudies Summary ORor RR (95% CI) Measure of heterogeneity Analysis
Q-value P value I2 Model

Study design
Cohort studies 9 1.23 (0.91, 1.67) 69.63 0.0001 0.89 RE
Case control studiesA 4 1.30 (1.09, 1.56) 9.56 0.02 0.69 RE
Cohort studies
Air dioxin-related toxicantsexposure and adversepregnancy outcome 4 0.99 (0.85, 1.16) 4.17 0.24 0.28 FE
Food dioxin-related toxicantsexposure and
Spontaneous abortion 2 1.05 (0.80, 1.37) 1.30 0.25 0.23 RE
Low birth weight 2 1.55 (1.24, 1.94) 0.41 0.52 0 RE
Case control studies
Maternal solid contaminantsdioxin exposure and birth defects 3 1.24 (1.19, 1.29) 1.52 0.47 0 FE

RE; Random-effect model, FE; Fixed-effect model, I2; Index of inconsistency and A; Cannot extract effective data from two studies [Dimich-Ward et al. (32), Eskenazi et al. (17)].