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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Drug Saf. 2015 Feb;38(2):183–187. doi: 10.1007/s40264-014-0255-7

Table 1.

Patient baseline demographic characteristics

Characteristic With anaphylaxis Without anaphylaxis p value
n 6 91
Age [years; mean (range)] 48.5 (43-55) 57 (21-87) 0.12
Sex: male [n (%)] 4 (66.6) 65 (71.4) 0.81
Weight [kg; mean (range)] 86.85 (55.6-124.6) 85.7 (47.3-164) 0.92
Diagnosis [n (%)]
    Acute leukaemia 0 (0) 22 (24.2) 0.33
    Chronic leukaemia 0 (0) 6 (6.6) 1.0
    Multiple myeloma 5 (83.3) 41 (45.0) 0.09
    Other 1 (16.7) 22 (24.2) 1.0
Baseline uric acid [mg/dL; mean (range)] 8.85 (7.5-10.2) 9.44 (5.1-18.1) 0.47
Baseline serum creatinine [mg/dL; mean (range)] 2.56 (1.33-5.28) 2.12 (0.67-8.66) 0.45
Tumour lysis syndrome [n (%)] 1 (16.6) 34 (37.4) 0.41
Lactate dehydrogenase [IU/L; mean (range)] 646 (174-2109) 434 (83-2481) 0.32
Rasburicase dose [mg; mean (range)] 3.5 (3-6) 3.07 (3-6) 0.96
Rasburicase dose [mg/kg; mean (range)] 0.042 (0.024-0.064) 0.038 (0.018-0.085) 0.32