Table 1.
Characteristic | With anaphylaxis | Without anaphylaxis | p value |
---|---|---|---|
n | 6 | 91 | |
Age [years; mean (range)] | 48.5 (43-55) | 57 (21-87) | 0.12 |
Sex: male [n (%)] | 4 (66.6) | 65 (71.4) | 0.81 |
Weight [kg; mean (range)] | 86.85 (55.6-124.6) | 85.7 (47.3-164) | 0.92 |
Diagnosis [n (%)] | |||
Acute leukaemia | 0 (0) | 22 (24.2) | 0.33 |
Chronic leukaemia | 0 (0) | 6 (6.6) | 1.0 |
Multiple myeloma | 5 (83.3) | 41 (45.0) | 0.09 |
Other | 1 (16.7) | 22 (24.2) | 1.0 |
Baseline uric acid [mg/dL; mean (range)] | 8.85 (7.5-10.2) | 9.44 (5.1-18.1) | 0.47 |
Baseline serum creatinine [mg/dL; mean (range)] | 2.56 (1.33-5.28) | 2.12 (0.67-8.66) | 0.45 |
Tumour lysis syndrome [n (%)] | 1 (16.6) | 34 (37.4) | 0.41 |
Lactate dehydrogenase [IU/L; mean (range)] | 646 (174-2109) | 434 (83-2481) | 0.32 |
Rasburicase dose [mg; mean (range)] | 3.5 (3-6) | 3.07 (3-6) | 0.96 |
Rasburicase dose [mg/kg; mean (range)] | 0.042 (0.024-0.064) | 0.038 (0.018-0.085) | 0.32 |