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. 2015 Mar 10;6:6404. doi: 10.1038/ncomms7404

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(a) Reproducible CHD8-binding sites identified in two biological replicates of hNSC, midfetal human brain and embryonic day 17.5 mouse cortex. The number of reproducible sites in each tissue and the subset identified in both tissues are indicated in each section of the Venn diagram. The number of ASD risk genes from Liu et al. bound by CHD8 in each subset is noted in parentheses. (b) Histogram showing the results of ASD risk gene label permutations (n=10,000, green bars) assessing enrichment of ASD risk genes reported by Liu et al. within conserved CHD8 target genes. (c) Selected gene ontology categories reported by DAVID36 as enriched in the set of genes bound by CHD8 in hNSC, midfetal human brain and mouse cortex. P values were corrected for multiple testing using the Benjamini–Hochberg method.