Ratios of venous to arterial plasma Aβ concentrations by 3 assays: IP/MS, ELISA, and xMAP. Central indicates veins draining the brain capillary bed and includes measurements from the internal jugular vein (IJ), sigmoid sinus (SS), left inferior petrosal sinus (IPSL), and right inferior petrosal sinus (IPSR). Peripheral represents measurements from the peripheral femoral vein (PV). *p < 0.01, ns = not significant. Error bars denote 95% confidence intervals.