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. 2015 Mar 8;12:47. doi: 10.1186/s12974-015-0261-4

Figure 2.

Figure 2

The effect of central infusion of AT2-R antagonist PD123,319 on DOCA/salt-induced hypertension in female rats. Daily mean arterial pressures (MAP) (A) and heart rate (HR) (B) before and during DOCA/salt treatments in intact females with or without central infusions of PD123,319. (C,D). Average changes in MAP and HR induced by DOCA/NaCl treatment in all groups. *P < 0.05 compared to baseline, # P < 0.05 compared to females with central infusion of PD123,319. DOCA, deoxycorticosterone acetate; icv, intracerebroventricular.