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. 2015 Mar 8;12:47. doi: 10.1186/s12974-015-0261-4

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© Dai et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Representative Western blots and quantitative comparison of protein levels for renin-angiotensin system components (renin, AT1-R, AT2-R, ACE-1, ACE-2) (A,B) and inflammatory cytokines (TNF-α, IL-1β and IL-10) (C,D) in the PVN in each group of intact females. Values are corrected by β-actin and expressed as mean ± SEM (n = 5 for each group). *P < 0.05 compared to control females, ^† P < 0.05 compared to central vehicle plus systemic DOCA/salt. Con, control; DOCA, deoxycorticosterone acetate; icv, intracerebroventricular; PVN, paraventricular nucleus; AT, angiotensin receptor type; ACE, angiotensin-converting enzyme; IL, interleukin; TNF, tumor necrosis factor.