Table 2.
Demographic data.
| A1+ | A1− | ||
|---|---|---|---|
| COHORT 1 | |||
| Women/Men (n = 87) | 17/20 | 26/24 | χ2 = 0.31, p = 0.577 |
| Mean age (n = 87) | 24.9 ± 3.6 | 24.3 ± 2.6 | t(85) = 0.83, p = 0.410 |
| Smokers/Nonsmokers (n = 87) | 15/22 | 14/36 | χ2 = 1.51, p = 0.220 |
| COMT mm/vm/vv (n = 87) | 13/14/10 | 18/15/17 | χ2 = 0.73, p = 0.694 |
| DAT1-VNTR 9+/9− (n = 85) | 11/25 | 15/34 | χ2 < 0.01, p = 0.996 |
| C957T CC/CT/TT (n = 87) | 11/19/7 | 8/24/18 | χ2 = 4.04, p = 0.132 |
| DARPP-32 CC/CT/TT (n = 87) | 4/13/20 | 3/18/29 | χ2 = 0.68, p = 0.714 |
| COHORT 2 | |||
| Women/Men (n = 95) | 13/21 | 35/26 | χ2 = 3.20, p = 0.074 |
| Mean age (n = 95) | 25.2 ± 3.3 | 24.2 ± 2.4 | t(93) = 1.58, p = 0.121 |
| Smokers/Nonsmokers (n = 95) | 5/29 | 14/47 | χ2 = 0.93, p = 0.335 |
| COMT mm/vm/vv (n = 95) | 11/14/9 | 19/27/15 | χ2 = 0.09, p = 0.957 |
| DAT1-VNTR 9+/9− (n = 93) | 17/17 | 32/27 | χ2 = 0.16, p = 0.693 |
| C957T CC/CT/TT (n = 95) | 15/17/2 | 3/37/21 | χ2 = 25.49, p < 0.001 |
| DARPP-32 CC/CT/TT (n = 95) | 3/15/16 | 0/20/41 | χ 2 = 7.62, p = 0.022 |
Gender distribution, age (means ± standard deviations), number of smokers and nonsmokers. Allelic distributions for following polymorphisms: COMT Val108/158Met (mm, met homozygotes; vm, val/met heterozygotes; mm, met homozygotes), DAT1-VNTR (9+: carriers of the 9-repeat allele 9/9 and 9/10; 9−: 10-repeat homozygous subjects 10/10), C957T (CC/CT/TT carriers), and DARPP-32 (CC/CT/TT carriers). A1+, carriers of the A1 allele; A1−, A2 homozygotes.