Fig. 1.

Effects of fluoxetine (10 mg/kg) and uncontrollable tail shock stress on freezing behavior immediately before (pre-shock) and immediately following (representing fear conditioned to contextual or discrete cues in the shuttle box) three foot shocks in a shuttle box. Fluoxetine was administered 1 h and tail shock stress 24 h prior to behavioral testing. Data are presented as a 2-min blocks of freezing and b the mean percent shock-elicited freezing for the entire 20-min observation period. Data represent means ± SEM. Asterisks p<0.05 relative to saline-treated rats; theta p<0.05 relative to fluoxetine-treated rats. The number in each bar represents the number of animals included in that group