FIG. 6.

MSCs treatments induce the proliferation of liver parenchymal cells. (A–C) Representative microphotographies of PCNA immunostained liver sections from saline (A), AdGFP-MSCs (B), and AdIGF-I-MSC-(C) treated mice (scale bars: 50 μm). (D) Quantification of liver PCNA immunostained cells at 1, 3, and 14 days after saline (white bars), AdGFP-MSCs (gray bars) or AdIGF-I-MSCs (black bars) administration. (E) Quantification of percentage of hepatocytes expressing PCNA on total population of cells expressing this marker. ^σP<0.05; **P<0.01; ***^σσσP<0.001; * versus saline; ^σ versus AdGFP-MSCs.